Montmorillonite K-10 catalyzed Mannich reaction: Synthesis of aminonaphthoquinone derivatives from Lawsone
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چکیده
منابع مشابه
Novel Aminonaphthoquinone Mannich Bases Derived from Lawsone and their Copper(II) Complexes: Synthesis, Characterization and Antibacterial Activity
Uma série de novas Bases de Mannich (HL1-HL13) derivadas da 2-hidroxi-1,4-naftoquinona (lausona), benzaldeídos substituídos [C 6 H 2 RRRC(O)H] e várias aminas primárias (NH 2 R, R = n-butil, benzil, alil, 2-furfuril) e seus complexos de Cu, [Cu(L1) 2 ]-[Cu(L13) 2 ], foram sintetizados e caracterizados por métodos analíticos e espectroscópicos. As estruturas dos complexos 1 (R = R = R = H; R = B...
متن کاملAminonaphthoquinone Mannich Bases Derived from Lawsone and Their Copper(II) Complex Derivatives: Synthesis and Potential Cholinesterase Inhibitors as Identified by On-flow Assay
A new series of Mannich bases derived from 2-hydroxy-1,4-naphthoquinone (lawsone), substituted benzaldehydes and two primary amines, and their Cu complexes were synthesized and evaluated for their potential as selective cholinesterase inhibitors (ChEIs). Immobilized capillary enzyme reactors (ICERs) bearing butyrylcholinesterase (BChE) and acetylcholinesterase (AChE) were used not only for the ...
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A new chemoselective reductive nitro-Mannich cyclization reaction sequence of nitroalkyl-tethered lactams has been developed. Relying on the rapid and chemoselective iridium(I)-catalyzed reduction of lactams to the corresponding enamine, subsequent nitro-Mannich cyclization of tethered nitroalkyl functionality provides direct access to important alkaloid natural-product-like structures in yield...
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Substituted 1, 2, 4- Triazoles have shown multiple biological activities such as anti-inflammatory, anti fungal, etc. 5-mercapto triazoles were prepared from the potassium dithiocarbazinates. These triazoles were used for preparation of different derivatives by two different schemes. In the first scheme the Mannich bases were prepared from 5- marcapto-s triazole Quinazolines. The 5-Marcato-s-Tr...
متن کاملChiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles
A highly diastereo- and enantioselective Mannich-type reaction of 3-aryloxindoles with N-Boc aldimines was achieved under the catalysis of axially chiral ammonium betaines. This catalytic method provides a new tool for the construction of consecutive quaternary and tertiary stereogenic carbon centers on biologically intriguing molecular frameworks with high fidelity.
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ژورنال
عنوان ژورنال: Synthetic Communications
سال: 2018
ISSN: 0039-7911,1532-2432
DOI: 10.1080/00397911.2018.1466334